Amazing Structural Similarity: Linezolid and Rivaroxaban

Factor Xa inhibitor Xarelto, developed as a new anticoagulant, has a really amazing structural similarity to Zyvox, BUT it does not have antibacterial activity against Gram positive pathogens as most oxazolidinones do. This pair should be used as an excellent example to teach "Similarity". Be open minded, only SAR can guide you!